Mouse Monoclonal Antibody to Apoa5 (bd)

Item#:

sAP-0005

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0005
Product Name	Mouse Monoclonal Antibody to Apoa5 (bd)
Target Molecle	Apoa5 (bd)
Aliases	RAP3; APOAV; APOA-V
Species	Human;
MW	41.2kDa
Enterez GeneID	116519
General Information	Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglyc erides, whereas a knock-in model with human ApoA5 produced 50¿70% lower ; ; concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Immunogen	Purified recombinant fragment of human APOA5 (AA
Clone	MM4H8H8E2(c);
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Hoppe-Seyler's Z. et al. Physiol. Chem. 354