| Product Name | Soluble RANK Ligand (158-316 a.a) Mouse Recombinant |
| Synonyms | Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf. |
| Description | sRANKL Mouse Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain (158-316 a.a) having a molecular mass of 19kDa.The sRANKL is purified by proprietary chromatographic techniques. |
| Uniprot Accesion Number | Q3TWY5 |
| Amino Acid Sequence | Lys158-Asp316, with an N-terminal Met, Accession # Q3TWY5. |
| Source | Escherichia Coli. |
| Physical Appearance and Stability | Lyophilized sRANKL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution sRANKL should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Formulation and Purity | sRANKL protein was lyophilized from a 0.2µm filtered solution in NaH2PO4, NaCl and EDTA. Greater than 95.0% as determined by SDS-PAGE. |
| Application | |
| Solubility | It is recommended to reconstitute the lyophilized sRANKL in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Biological Activity | The ED50, as measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells, is less than 2ng/ml. |
| Shipping Format and Condition | Lyophilized powder at room temperature. |
| Usage Statement | Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
