Goat anti-THRB Antibody |
| Principle Name | THRB |
| Official Symbol | THRB |
| All Name and Symbols | THRB; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); ERBA-BETA; ERBA2; GRTH; MGC126109; MGC126110; NR1A2; THR1; THRB1; THRB2; avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2; generalize |
| Accession Number(s) | NP_000452.2 |
| Peptide Sequence | REELQKSIGHKP, is from internal region |
| Human Gene ID(s) | 7068 |
| Non-Human GeneID(s) | 21834 (mouse); 24831 (rat); |
| Important Comments | This antibody is not expected to cross-react to THRA. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 32000. |
| Western Blot | Approx 50+60kDa bands observed in Human Bone Marrow lysates (calculated MW of 52.8kDa according to NP_NP_000452.2 and of 54.5kDa according to EAW64350.1). Recommended concentration |
| Reference(s) | Kim JH, Park TS, Baek HS, Kim GH, Yoo HW, Park JH. A newly identified insertion mutation in the thyroid hormone receptor-beta gene
in a Korean family with generalized thyroid hormone resistance. J Korean Med Sci. 2007 Jun;22(3) |
