Goat anti-LYN Antibody |
| Principle Name | LYN |
| Official Symbol | LYN |
| All Name and Symbols | LYN ; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog ; FLJ26625 ; JTK8; Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog |
| Accession Number(s) | NP_002341.1 |
| Peptide Sequence | KTQPVRNTERT , is from internal region |
| Human Gene ID(s) | 4067 |
| Non-Human GeneID(s) | |
| Important Comments | |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 16000. |
| Western Blot | Approx 60kDa band observed in lysates of cell line U937 (calculated MW of 58.6kDa according to NP_002341.1). Recommended concentration |
| Reference(s) | Okamoto M, Hayakawa F, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T. Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. Leukemia. 2007 Mar;21(3) |
