Goat anti-CLN2 / TPP1 Antibody

Item#:

dAP-1854

Size	Price	Quantity
50.0 ug	$310.00

Goat anti-CLN2 / TPP1 Antibody
Principle Name	CLN2 / TPP1
Official Symbol	TPP1
All Name and Symbols	TPP1; tripeptidyl peptidase I; CLN2; GIG1; LPIC; MGC21297; ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease); growth-inhibiting protein 1; lysosomal pepstatin insensitive protease; tripeptidyl aminopeptidase; tripeptidyl-pept
Accession Number(s)	NP_000382.3
Peptide Sequence	TPSVIRKRYNLTSQD, is from internal region
Human Gene ID(s)	1200
Non-Human GeneID(s)	12751 (mouse);
Important Comments
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As	lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications	Pep ELISA, WB
Tested Species	Human
Peptide ELISA	antibody detection limit dilution 1 to 4000.
Western Blot	Approx 65kDa band observed in Human Placenta lysates (calculated MW of 61.2kDa according to NP_000382.3). Recommended concentration
Reference(s)	Kousi M, Siintola E, Dvorakova L, Vlaskova H, Turnbull J, Topcu M, Yuksel D, Gokben S, Minassian BA, Elleder M, Mole SE, Lehesjoki AE. Mutations in CLN7/MFSD8 are a common cause of variant late-infantile neuronal ceroid lipofuscinosis. Brain