Mouse Monoclonal Antibody to SRA

Item#:

sAP-0057

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0057
Product Name	Mouse Monoclonal Antibody to SRA
Target Molecle	SRA
Aliases	SRAP; STRAA1
Species	Human
MW	N/A
Enterez GeneID	10011
General Information	Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
Immunogen	Purified recombinant fragment of SRA expressed in E. Coli.
Clone	MM1D4H8;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J. Chrencik, A. Brooun, M. Recht. Structure. 2006 Feb;14(2)