Mouse Monoclonal Antibody to Desmin

Item#:

sAP-0075

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0075
Product Name	Mouse Monoclonal Antibody to Desmin
Target Molecle	Desmin
Aliases	Desmin
Species	Human
MW	N/A
Enterez GeneID	1674
General Information	Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
Immunogen	Purified recombinant fragment of Desmin expressed in E. Coli.
Clone	MM10H7D2;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. George A. Ordway, Daniel J. Garry. J. Exp. Biol., Sep 2004; 207