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Mouse Monoclonal Antibody to DAXX
Item#:
sAP-0320
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0320
Product Name Mouse Monoclonal Antibody to DAXX
Target Molecle DAXX
Aliases DAP6; EAP1; BING2
Species Human
MW 81kDa
Enterez GeneID 1616
General Information DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Immunogen Purified recombinant fragment of human DAXX expressed in E. Coli.
Clone MM7A11;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Antibody are purified by protein G affinity chromatography. ; Liquid in PBS containing 50% glycerol and 0.03% sodium azide. ;
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Stem Cells Dev. 2005 Aug;14(4)
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