Mouse Monoclonal Antibody to C-CBL

Item#:

sAP-0600

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0600
Product Name	Mouse Monoclonal Antibody to C-CBL
Target Molecle	C-CBL
Aliases	CBL; CBL2; NSLL; C-CBL; RNF55
Species	Human; Mouse; Rat
MW	120kDa
Enterez GeneID	867
General Information	The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Immunogen	Purified recombinant fragment of human C-CBL expressed in E. Coli.
Clone	MM3B12;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Exp Cell Res. 2009 Jul 1;315(11)