Mouse Monoclonal Antibody to Phospho-4E-BP1 (Ser65)

Item#:

sAP-1505

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1505
Product Name	Mouse Monoclonal Antibody to Phospho-4E-BP1 (Ser65)
Target Molecle	Phospho-4E-BP1 (Ser65)
Aliases	EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I
Species	Human;
MW	12.6kDa
Enterez GeneID	1978
General Information	This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Immunogen	Synthesized peptide of human Phospho-4E-BP1 (Ser65).
Clone	MM1E2E7
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.J Mol Biol. 2014 Oct 23;426(21)