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Mouse Monoclonal Antibody to CD122
Item#:
sAP-1723
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-1723
Product Name Mouse Monoclonal Antibody to CD122
Target Molecle CD122
Aliases IL2RB; IL15RB; P70-75
Species Human;
MW 61kDa
Enterez GeneID 3560
General Information The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
Immunogen Purified recombinant fragment of human CD122 (AA
Clone MM1G11C6
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Curr Opin Hematol. 2015 Jan;22(1)
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